Dr Andrew Evans - The Royal Melbourne Hospital

Dr Andrew Evans - The Royal Melbourne Hospital

Davis Auditorium
Start Time: 
Wed, 04/12/2019 - 1:00pm
End Time: 
Wed, 04/12/2019 - 2:00pm

Stem Cell therapies for neurodegenerative disease

Clinical Translation seminar hosted by Associate Professor John Wentworth​

Parkinson’s disease is the second most common neurodegenerative disease and it’s worldwide prevalence is predicted to double in the next 25 years. Unfortunately, the pharmacologic treatment of Parkinson disease (PD) is currently limited to symptomatic therapies. For PD, therapy that is disease-modifying or neuroprotective therapies is still theoretical as the complex mechanisms that result in the death of the 300 to 400 thousand at risk neurones are poorly understood. It is hoped that emerging techniques of dopamine cell replacement with stem cells may provide the elusive treatment that either slows the progress of the disease or may help reverse some of the symptoms. In this seminar, the current challenges and developments in cellular replacement therapies will be discussed using an example of a phase one study conducted through the Royal Melbourne Hospital.

Andrew specialised in neurology at the Royal Melbourne and Western Hospitals and the Kingston Centre and then carried out a movement disorders fellowship at the National Hospital for Neurology and Neurosurgery, Queen Square, London where he completed a doctoral thesis in Nonmotor symptoms of Parkinson's disease. He is currently Director of Movement Disorders at the Royal Melbourne Hospital and is an Honorary Senior Fellow and Lecturer with the University of Melbourne and WEHI. He has published broadly on a range of clinical and translational facets of a range of Neurodegenerative disorders.

He specializes in management and treatment of Parkinson’s patients and other movement disorder patients, offering a range of device-aided therapies to patients with Parkinson’s disease including Deep Brain Stimulation.