Targeting the immune system in cancer

Targeting the immune system in cancer

Project details

Recently there has been massive growth in the use of immunotherapy, harnessing the power of a patient’s own immune system to target cancer. This project will focus on the computational analysis of large cancer data sets to identify markers which may help with predicting patient response to immunotherapy, and to identify genes which could be targeted for novel immunotherapeutics. The project will also explore and model interactions between cancer cells and the immune system to identify potential targets for increasing cancer immunogenicity. 

This project is ideal for a student who wishes to develop their skills in bioinformatics and computational biology, and to increase their understanding of immune function in cancer. 

About our research group

The Davis laboratory is a computational biology group which is focused on exploring features of cancer progression, including regulatory programs such as epithelial-mesenchymal transition. We have a general interest in how cancerous cells hijack various regulatory mechanisms that allow unregulated growth or confer the ability to metastasize and form new tumors. While our laboratory has an established breast cancer research program, we have a general interest in different cancer types. 

The Huntington laboratory aims to understand how the many diverse types of white blood cells develop, and how constant numbers of these cells are maintained throughout our life. The laboratory is located in the Clinical Translation Centre within the Institute, facilitating investigations into human models of disease, including cancer.



Dr Melissa Davis

Portrait photo of Dr Melissa Davis
Joint Division Head
Joe Cursons
Bioinformatics division

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