High resolution 3-dimensional imaging to characterise metastatic cancers

High resolution 3-dimensional imaging to characterise metastatic cancers

Project details

Metastatic tumors are associated with a poor prognosis in patients with cancer. Advances in fluorescence labelling methods, imaging technologies and computational strategies (eg. machine learning) are allowing the structure and function of cells and tissues to be interrogated with greater detail than ever before. 

This study aims to use cutting-edge microscopy techniques to study cell behavior and the organelle interactome in highly metastatic cancer cells. Students will have an opportunity to apply a variety of approaches to gain greater insights into how cancers are able to spread and invade different areas of the body.  

About our research group

This project will be undertaken in the Centre for Dynamic Imaging. The design and use of cutting edge imaging technologies will be led by Drs Kelly Rogers and Verena Wimmer who have many years of expertise in 3 and 4-dimensional microscopy. The work will be undertaken in collaboration with Dr Delphine Merino, from the ONJCRI, head of the ‘Tumour Progression and Heterogeneity’ laboratory, whose major focus is on breast cancer metastasis and who has access to various tumour models from patients. 

Researchers:

Dr Kelly Rogers

Dr Kelly Rogers
Dr
Kelly
Rogers
Head, Imaging Laboratory
Dr Delphine Merino
Dr
Delphine
Merino
Olivia Newton-John Cancer Research Institute
Verena Wimmer profile picture
Dr
Verena
Wimmer
Systems Biology and Personalised Medicine division

Project Type: