Dr Hui-Li Wong

Honorary Clinical Research Fellow
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I am a medical oncologist at the Peter MacCallum Cancer Centre and clinical research fellow at the Walter and Eliza Hall Institute. My areas of expertise are gastrointestinal cancers and cancers of unknown primary.

My research focus is on the use of real-world data to examine treatment and outcomes in routine practice, facilitate research and improve the quality of care for patients. Over the past 10 years, I have been involved in running a large multi-centre registry collecting comprehensive treatment and outcome data for colorectal cancer. I also led the implementation of the registry-based randomised trials program as part of the Victorian Comprehensive Cancer Centre’s research initiative, examining the feasibility of this pragmatic clinical trial approach to increase trial participation for cancer patients. I am currently part of a team of investigators working on a new model of care to support the earlier diagnosis of cancers of unknown primary.


Selected publications from Dr Hui-Li Wong

Cohen JD, Li L, Wang Y, Thorburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolgfang CL, Goggins MG, Molin MD, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz L, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N. Detection and localization of surgically resectable cancers with a multi-analyte liquid biopsy. Science. 2018 Feb 23. 359(6378):926-930. PMID: 29348365

Wong HL, Yang KC, Shen Y, Zhao EY, Loree JM, Kennecke HF, Kalloger SE, Karasinska JM, Lim HJ, Mungall AJ, Feng X, Davies JM, Schrader K, Zhou C, Karsan A, Jones SJM, Laskin J, Marra MA, Schaeffer DF, Gorski SM, Renouf DJ. Molecular characterisation of metastatic pancreatic neuroendocrine tumours (PNETs) using whole genome and transcriptome sequencing. Cold Spring Harb Mol Case Stud. 2018 Feb 1;4(1). doi: 10.1101/mcs.a002329, Feb 2018. PMID: 29092957

Rohr UP, Herrmann P, Ilm K, Zhang H, Lohmann S, Reiser A, Muranyi A, Smith J, Burock S, Osterland M, Leith K, Singh S, Brunhoeber P, Bowermaster R, Tie J, Christie M, Wong HL, Waring P, Shanmugam K, Gibbs P, Stein U. Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies. Ann Oncol. 2017 Aug 1;28(8) doi: 10.1093/annonc/mdx207. PMID: 28460000

Wong HL, Lee B, Field K, Lomax A, Tacey M, Shapiro J, McKendrick J, Zimet A, Yip D, Nott L, Jennens R, Richardson G, Tie J, Kosmider S, Parente P, Lim L, Cooray P, Tran B, Desai J, Wong R, Gibbs P. Impact of primary tumor site on bevacizumab efficacy in metastatic colorectal cancer. Clin Colorectal Cancer. 2016 Jun;15(2):39-315. PMID: 26968236

Field K, Wong HL, Shapiro J, et al. Developing a national database for metastatic colorectal cancer management: perspectives and challenges. Intern Med J 2013 Nov;43(11):1224-31 PMID: 23834128

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