Professor Tim Stinear - Doherty Applied Microbial Genomics Centre

Professor Tim Stinear - Doherty Applied Microbial Genomics Centre

Location: 
Cory Theatre - GTAC
Start Time: 
Thu, 16/05/2019 - 6:30pm
End Time: 
Thu, 16/05/2019 - 7:30pm

​The rise of Mycobacterium ulcerans disease (Buruli ulcer) around
Melbourne

ANZAAS lecture

Buruli ulcer (BU) causes a terrible, destructive skin and soft tissue
infection that can lead to permanent deformity and disability. Buruli
ulcer is caused by infection with the bacterium, Mycobacterium
ulcerans. Cases of the disease are reported in more than 30 countries but have been exponentially increasing locally around Melbourne, with potential for a sustained epidemic to affect thousands of Victorians. Investigations over the past 15 years have shown that Australian native possums are wildlife reservoirs of M. ulcerans and that mosquitoes are likely vectors that spread the disease to humans. Detailed analysis of hundreds of M. ulcerans isolates obtained from patients over the last sixty years has revealed the likely origins and pattern of spread of M. ulcerans in Victoria. These new insights from research have created the first opportunities to test public health intervention strategies that will stop the spread of this disease.

Professor Tim Stinear is Scientific Director of the Doherty Applied Microbial Genomics Centre and leads a team of scientists focused on understanding how bacteria spread and cause disease. He did his PhD at Monash University in 2001, followed by a three-year postdoctoral period at the Pasteur Institute in Paris, France. During this time, Tim determined the first complete genome sequence for Mycobacterium ulcerans.