WEHI Parkinson’s Disease Special Seminar hosted by Sylvie Callegari & Grant Dewson

Professor Charalampos Tzoulis

Head, Neuromics Research Group, University of Bergen; Director, K.G Jebsen Center for Translational Research in Parkinson’s disease, Norway

NAD replenishment therapy in Parkinson’s disease: A New Hope? 

Join via ZOOM

Webinar ID: 860 5003 4685

Passcode: 005958

Including Q&A session

Charalampos Tzoulis, is Professor of Neurology and Neurogenetics at the University of Bergen and Haukeland University Hospital, Norway. He is a clinical neurologist, and expert on movement disorders and neurodegeneration, including dementia and parkinsonism. His research focuses on exploring the role of mitochondrial dysfunction in Parkinson’s disease, with the aim to improve patient diagnosis and develop neuroprotective therapies. Currently, he is also co-Director of the Neuro-SysMed Center of Excellence for Clinical Research in Neurological diseases, where he leads the research on Parkinson’s disease and other neurodegenerative disorders.


Current treatments for Parkinson’s make no substantial impact on disease progression and despite several candidate neuroprotective therapies showing encouraging preclinical results, these have failed to show disease-modifying effects in clinical trials. A growing body of evidence suggests that therapies targeting mitochondria and NAD metabolism may confer neuroprotective effects in Parkinson’s. This presentation will cover hallmark experimental evidence supporting these hypotheses, and illustrate how basic laboratory research led to the first clinical trial of NAD replenishment therapy in Parkinson’s, which showed encouraging results (Cell Metabolism, Brakedal et al., doi: 10.1016/j.cmet.2022.02.001)

All welcome!