Len Harrison-Publications

Len Harrison-Publications

Publications

  1. Zhang Y, Kinkel S, Maksimovic J, Bandala-Sanchez E, Tanzer MC, Naselli G, Zhang JG, Zhan Y, Lew AM, Silke J, Oshlack A, Blewitt ME, Harrison LC (2014) The polycomb repressive complex 2 governs life and death of peripheral T cells. Blood 124:737-749. PMID 24951427.
  2. Zhang Y, Maksimovic J, Naselli G, Qian J, Blewitt ME, Oshlack A, Harrison LC (2013). Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood 122:2823-2836. PMID 23974203
  3. Bandala-Sanchez E, Zhang Y, Reinwald  S, Dromey JA, Lee B-H, Qian J, Böhmer RM, Harrison LC (2013). T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10. Nat Immunol 14:741-748. PMID: 23685786
  4. Harrison LC, Wentworth JM, Zhang Y, Bandala-Sanchez E, Böhmer RM, Neale AM, Stone NL, Naselli G, Bosco JJ, Auyeung P, Rashidi M, Augstein P, Morahan G (2013) Antigen-based vaccination and prevention of type 1 diabetes. Curr Diab Reports 13: 616-623. PMID: 23888323
  5. Roep BO, Solvason N, Gottlieb PA, Abreu JRF, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King R, Robinson WH, Utz PJ, Garren H, The BHT 3021 Investigators and Steinman L (2013). Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes. Science Trans Med 5:191ra82 (pp 1-9). PMID: 23803704
  6. Fourlanos S, Perry C, Gellert SA, Martinuzzi E, Mallone R, Butler J, Colman PG, Harrison LC (2011) Evidence that nasal insulin induces immune tolerance to insulin in adults with autoimmune diabetes. Diabetes 60:1237-45. PMID: 21307076
  7. Dromey JA, Lee BH, Yu H, Young HE, Thearle DJ, Jensen KP, Mannering SI, Harrison LC (2011). Generation and expansion of regulatory human CD4+ T-cell clones specific for pancreatic islet autoantigens. J Autoimmunity 36: 47-55. PMID: 21050716
  8. Wentworth JM, Naselli G, Brown WA, Doyle L, Wabitsch M, O’Brien PE, Harrison LC (2010). Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes 59:1648-56. PMID: 20357360
  9. Honeyman MC, Stone NL, Falk BA, Nepom G, Harrison LC (2010). Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens. J Immunol 184:2204-10. PMID: 20083660
  10. Wentworth JM, Fourlanos S, Harrison LC (2009).  Reappraising the stereotypes of diabetes in the modern diabetogenic environment. Nature Rev Endocrinol  5: 483-489. PMID: 19636326