Leigh Coultas-Publications

Leigh Coultas-Publications

Researcher: 

Selected publications

  1. Watson EC, Grant ZL, Coultas L. Endothelial cell apoptosis in angiogenesis and vessel regression. Cell Mol Life Sci. 2017 Jun. PMID: 28646366
  2. Watson EC, Koenig MN, Grant ZL, Whitehead L, Trounson E, Dewson G, Coultas L. Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis. Development. 2016 Jul 28. PMID: 27471260.
  3. Watson EC, Whitehead L, Adams RH, Dewson G, Coultas L. Endothelial cell survival during angiogenesis requires the pro-survival protein MCL1. Cell Death Differ. 2016 Aug;23(8):1371-9 PMID: 26943318
  4. Okamoto T, Coultas L, Metcalf D, van Delft MF, Glaser SP, Takiguchi M, Strasser A, Bouillet P, Adams JM, Huang DC. Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):261-6. PMID: 24363325.
  5. Koenig MN, Naik E, Rohrbeck L, Herold MJ, Trounson E, Bouillet P, Thomas T, Voss AK, Strasser A, Coultas L. Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3. Cell Death Differ. 2014 Jun 27;21:1687-95 PMID: 24971484.
  6. Naik E, O'Reilly LA, Asselin-Labat ML, Merino D, Lin A, Cook M, Coultas L, Bouillet P, Adams JM, Strasser A. Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells. J Exp Med. 2011 Jul 4;208(7):1351-8. PMID: 21646395.
  7. Coultas L, Nieuwenhuis E, Anderson GA, Cabezas J, Nagy A, Henkelman RM, Hui CC, Rossant J. Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms. Blood. 2010 Jul 29;116(4):653-60. PMID: 20339091.
  8. Walls JR, Coultas L, Rossant J, Henkelman RM. Three-dimensional analysis of vascular development in the mouse embryo. PLoS ONE. 2008;3(8):e2853. PMID: 18682734.
  9. Hellstrom M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalen M, Gerhardt H, Betsholtz C. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007 Feb 15;445(7129):776-80. PMID: 17259973.
  10. Coultas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development. Nature. 2005 Dec 15;438(7070):937-45. PMID: 16355211.

 

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