Nancy Berliner, MD - Brigham and Women's Hospital, USA

Nancy Berliner, MD - Brigham and Women's Hospital, USA

VCCC Level 7 Lecture Theatre A
Start Time: 
Mon, 04/03/2019 - 11:00am
End Time: 
Mon, 04/03/2019 - 11:45am

​Hemophagocytic Lymphohistiocytosis in Adults

Special seminar hosted by Professor Andrew Roberts

Adult hematologists and internists have observed that the incidence of Hemophagocytic Lymphohistiocytosis (HLH) in adult patients appears to be increasing. Whether this represents a true increase in the occurrence of the disorder or a reflection of ascertainment bias remains uncertain. In any case, since most of the literature on HLH is based on observations of the pediatric population, there is an increasing focus on the significant differences in presentation, natural history, and appropriate intervention between adult and pediatric patients with HLH. I will provide an overview of HLH and try to provide a context for approaching the disease as it presents in the adult population.

Dr. Berliner is the H. Franklin Bunn Professor of Medicine and Chief of Hematology at the Brigham and Women’s Hospital. She received her medical degree from Yale Medical School, and obtained training as a Resident in Internal Medicine, Internal Medicine Chief Resident, and Hematology Fellow at the Brigham and Women’s Hospital in Boston, MA. She then spent 20 years on the faculty of the Yale University School of Medicine, where she rose through the ranks to Professor of Internal Medicine and Genetics. She has broad clinical interests in both classical hematology and hematologic malignancies. Her research is focused on the regulation of neutrophil-specific gene expression and its disruption in myelodysplasia and acute leukemia, and on the pathogenesis of anemia in the elderly. She has served on the Editorial Boards of Blood, the European Journal of Hematology, and the American Journal of Hematology. She received the Stohlman Prize from the Leukemia/Lymphoma Society of America. She is a member of the Institute of Medicine, American Clinical and Climatological Society, the American Society for Clinical Investigation, the Association of American Physicians, and the Interurban Clinical Club, and is a fellow of the American Association for the Advancement of Science and the American College of Physicians.  She was elected to the National Academy of Medicine in 2010. She was President of the American Society of Hematology in 2009 and is the current Deputy Editor of the journal Blood. In 2020, she will become the Blood Editor-in-Chief.