WEHI Special Seminar hosted by Professor Phil Hodgkin
Dr Marcus Robinson
Research Fellow, Immunology Alfred Hospital, Monash University
The regulation and propagation of antibody responses
Including Q&A session
Dr Robinson completed his PhD training with Graham Le Gros at the Malaghan Institute of Medical Research where he developed an especial interest in IgE biology. To pursue that interest, he undertook post-doctoral training in the IgE-centric lab of Chris Allen at UCSF. Following a successful period in Dr Allen’s lab, Dr Robinson moved to Monash University’s Immunology department, where he has worked since 2016, first as a post-doc and from 2021 as a group leader under David Tarlinton’s tutelage, investigating the initiation and propagation of antibody responses. Dr Robinson’s recent outputs highlight the importance of BCL6 in the selection of antigen-reactive B cells into immune responses (Cell Reports, 2020), and used an antibody-secreting plasma cell-timestamping reporter mouse to define the manner in which long-lived plasma cells are accrued (Science Immunology, 2022), and the rules governing the persistence of immunological memory (Immunity 2023). Dr Robinson maintains a focus on antibody responses in health, infection and vaccination settings, and continues to explore the regulation of IgE responses in allergy contexts. The seminar will cover Dr Robinson’s work addressing mechanisms of long-lived antibody secreting cell accrual, turnover and heterogeneity.