WEHI Wednesday Seminar hosted by Professors Jane Visvader & Geoff Lindeman

Associate Professor Kate Sutherland
Laboratory Head, ACRF Cancer Biology & Stem Cells division – Cancer Research & Treatments Theme, WEHI

Unlocking the heterogeneity of lung cancer for therapeutic discovery

 

Davis Auditorium

Join via SLIDO enter code #WEHIWednesday

Including Q&A session

Heterogeneity is a ‘hallmark’ of cancer, representing a significant obstacle on the path to a cure. Cancers are composed of unique molecular and functional states, which can influence all facets of tumour cell behaviour. In this seminar, Kate will introduce her research on the heterogeneity of KRAS mutant lung adenocarcinoma and small cell lung cancer. She will share the progress her laboratory has made in addressing cancer heterogeneity using biopsy samples from lung cancer patients and preclinical mouse models that recapitulate the human disease. Specifically, she will discuss leveraging these models to better understand tumour-intrinsic and -extrinsic processes that govern immune evasion and sensitivity to therapies. Deciphering these processes likely holds the key to achieving more durable therapy responses for patients.
 

Following her PhD studies, Kate joined the laboratory of Prof Anton Berns at The Netherlands Cancer Institute as an NHMRC CJ Martin and Marie Curie Incoming Postdoctoral Fellow. While there, she generated unique tools that led to the identification of the cells-of-origin of three main subtypes of lung cancer. Kate returned to WEHI as a Laboratory Head in the ACRF Cancer Biology and Stem Cells Division in 2013, where her team aims to understanding molecular mechanisms that underpin heterogeneity in lung cancer, with the goal of designing precision medicine approaches for lung cancer patients.
 

All welcome!