Dr Samuel Forster - Hudson Institute of Medical Research

Dr Samuel Forster - Hudson Institute of Medical Research

Location: 
Davis Auditorium
Start Time: 
Mon, 20/05/2019 - 12:00pm
End Time: 
Mon, 20/05/2019 - 1:00pm

Unlocking microbiome derived medicines: more than just sequencing

​Postgraduate lecture series hosted by Dr Greg Ebert

It is now clear the naturally occurring microbes that comprise the human microbiome play a key role in health and can directly and indirectly contribute to disease. With the advent of high-throughput sequencing approaches our understanding of these communities and their diverse composition has grown substantially. However, the emphasis has now shifted to understanding, with a particular focus on the individual species and strains that directly cause disease or could be used therapeutically. In this seminar I will discuss the technologies and methods for measuring the human microbiome and how we move from association based observational studies to the causative validation required for therapeutic development.

Dr Sam Forster leads the Microbiota and Systems Biology Laboratory within the Centre of Innate Immunity and Infectious Diseases at the Hudson Institute of Medical Research. His research group combines microbiology, immunology and computational biology to understand the role of gastrointestinal microbiota and determine ways to modify these communities to improve human health. This work has resulted in the development of methods to culture the majority of human gastrointestinal microbiota, advanced algorithms for metagenomics analysis and identification of rationally selected bacteriotherapy candidates.