Dr Marina Pajic - Garvan Institute of Medical Research

Dr Marina Pajic - Garvan Institute of Medical Research

Seminar Room 2
Start Time: 
Fri, 13/09/2019 - 1:00pm
End Time: 
Fri, 13/09/2019 - 2:00pm

​Understanding the molecular heterogeneity of pancreatic cancer: from mechanism to therapy

​Special seminar hosted by Dr Tracy Putoczki

Dr Marina Pajic completed her PhD in 2008 at the University of New South Wales Sydney, where she investigated chemoresistance mechanisms in childhood cancers. Dr Pajic’s postdoctoral work in the group of Professor Piet Borst at the Netherlands Cancer Institute (Amsterdam) led to discovery of key new mechanisms behind treatment-induced resistance in breast cancer.

Following her return to Australia in 2010 and collaborative efforts within the International Cancer Genome Consortium, Dr Pajic has established unique personalised medicine projects for pancreatic cancer and since 2013 leads the Personalised Cancer Therapeutics Lab at the Garvan Institute of Medical Research (Sydney). Her research focuses on the functional validation of tailored therapies for pancreatic cancer (Gut 2018, Science Translational Medicine 2017), delineating complex mechanisms behind treatment-induced resistance (Cancer Research 2018, Clinical Cancer Research 2017), and collaborations in cancer genomics and clinical research (Nature x7, Nature Comms 2018, J Clin Oncology, Gastroenterology 2017), with authoritative reviews for leading journals (Gastroenterology 2018).

The overall goal of her program is to understand the role of –omic alterations in pancreatic cancer progression and treatment failure and develop new effective treatment approaches.  Her research has been supported by three fellowships from the Cancer Institute New South Wales (2011- ongoing), current NHMRC Career Development Fellowship and Philip Hemstritch philanthropic fellowship, and project grant funding from the NHMRC, Cancer Australia, Cancer Council NSW and the Avner Pancreatic Cancer Foundation.