Dr Joanna Groom - Immunology division

Dr Joanna Groom - Immunology division

Start Time: 
Wed, 11/08/2021 - 1:00pm
End Time: 
Wed, 11/08/2021 - 2:00pm

WEHI Wednesday Seminar hosted by Associate Professor Daniel Gray


Dr Joanna Groom

Laboratory Head, Immunology division - Infection, Inflammation & Immunity Theme

Targeting T cell interactions for tailored immunity

Join via TEAMS

Including Q&A session


Activation and differentiation of T cells is an essential part of orchestrating the adaptive immune response. These processes determine precisely how responses are tailored towards the pathogen and if immune protection is established. During an infection, T cells dynamically interact with multiple, distinct cellular partners to determine their effector function and the formation of memory. For both CD4+ and CD8+ T cells, these cellular interactions link the extrinsic environment with the internal transcriptional networks that underpin T cell fate.  


Using examples for both CD4+ and CD8+ T cells, this seminar will outline our approach to discover, observe and direct the cellular interactions that control T cell fate. This knowledge will enable fit-for-purpose T cell differentiation; to stimulate potent T cell effector function for the elimination of chronic infection and cancer, or to amplify the formation of humoral immunity and longevity of cellular memory to prevent infectious diseases.  


All welcome!