A/Prof Matt Ritchie - Epigenetics & Development division

A/Prof Matt Ritchie - Epigenetics & Development division

Location: 
Davis Auditorium
Start Time: 
Wed, 25/05/2022 - 1:00pm
End Time: 
Wed, 25/05/2022 - 2:00pm

WEHI Wednesday Seminar hosted by Profess Marnie Blewitt

Associate Professor Matt Ritchie

Laboratory Head, Epigenetics & Development division – Healthy Development & Ageing Theme, WEHI



Adventures in nanopore sequencing: developing new tools for exploring methylation and isoform expression in development and cancer




Davis Auditorium

Online access via Slido
and enter code #WEHIWednesday

Including Q&A session




The application of Oxford Nanopore Technologies long-read sequencing in genomics research continues to expand. In this presentation I will highlight a number of tools we have developed to keep track of the myriad of analysis tools that are becoming available for long-read data (https://long-read-tools.org) along with software for visualising DNA methylation signal (NanoMethViz) and performing isoform analysis (FLAMES) in both bulk and single-cell transcriptomics data. Applications to studying imprinting in mouse development and exploring gene expression changes in different cell types in cancer will be presented, as well as future directions for this research.

 

All welcome!