Cell-specific gene expression in autistic and schizophrenic human brains (Masters option available)

Cell-specific gene expression in autistic and schizophrenic human brains (Masters option available)

Project details

The human brain consists of one of the most diverse collections of cell types. While researchers know about some of the functions these cells carry out in the normal brain, not much is known about the specific roles they play in neurological and psychiatric disorders, such as autism and schizophrenia.

The aim of this project is to learn more about cell-specific mechanisms causing schizophrenia and autism. To this end the student will utilise computational algorithms, currently under development in the lab, to establish cell-specific gene expression from transcriptomic data. Thus, the student will gain skills in the analysis of RNA-seq and microarray data, statistical techniques, method development and programming in R as well as become an expert in brain transcriptomics. 

About our research group

The Bahlo lab is a statistical genetics dry lab focused on the analysis of genomic data for both neurogenetics and infectious diseases. The lab has a strong track record in analysis of genomic and transcriptomic data as well as methods development of techniques to facilitate these analyses. It has developed software packages and web-tools.

The lab is vibrant with regular social outings and a fortnightly lab meeting. Presentation and attendance at conferences is encouraged. The lab has about 10 staff and students with four current PhD students and several Masters students.

Researchers:

Professor Melanie Bahlo

Melanie Bahlo
Professor
Melanie
Bahlo
Joint Division Head
Dr Saskia Freytag profile shot
Dr
Saskia
Freytag
Population Health and Immunity

Project Type: