Dr Giuseppe Infusini
Details
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Division: Systems Biology and Personalised Medicine
Research Overview
My research interest have involved the development of novel proteomics methodologies and mass spectrometry instrumentation, focusing on their applications in biological research with particular emphasis on proteins’ binding partners discovery, PTM characterisation, quantitative mass spectrometry and protein structural analysis.
Major Publications
- Kong X., Lin C., Infusini G., Oh H.B., Jiang H., Breuker K., Wu C.C., Charkin O.P., Chang H.C., McLafferty F.W., Numerous isomers of serine octamer ions characterized by infrared photodissociation spectroscopy. Chemphyschem. 2009 Oct 19;10(15):2603-6
- Fontanella B., Birolo L., Infusini G., Cirulli C., Marzullo L., Pucci P., Turco M.C., Tosco A., The co-chaperone BAG3 interacts with the cytosolic chaperonin CCT: new hints for actin folding. Int J Biochem Cell Biol. 2010 May;42(5):641-50.
- Perlman D.H., Bauer S.M., Ashrafian H., Bryan N.S., Garcia-Saura M.F., Lim C.C., Fernandez B.O., Infusini G., McComb M.E., Costello C.E., Feelisch M. Mechanistic Insights into Nitrite-Induced Cardioprotection Using an Integrated Metabonomic-Proteomic Approach. Circ Res. 2009 Mar 27; 104(6):796-804
- Makkinje A., Near R. I., Infusini G., Borre P.V., Bloom A., Cai D., Costello C.E., Lerner A. AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern. Cell Signal. 2009 Sep; 21(9)1423-35
- McLafferty F.W., Breuker K., Jin M., Han X., Infusini G., Jiang H., Kong X., Begley T.P. Top- down MS, a powerful complement to the high capabilities of proteolysis proteomics. FEBS J. 2007 Dec; 274(24):6256-68. Epub 2007 Nov 16.
- Casbarra A., Birolo L., Infusini G., Dal Piaz F., Svesson M., Pucci P., Svanborg C., Marino G., Conformational analysis of HAMLET, The folding variant of human alpha-lactalbumin associated with apoptosis. Protein Sci. 2004 May; 13(5):1322-30
