PhD and Honours projects: 2012 intake | Walter and Eliza Hall Institute of Medical Research

PhD and Honours research projects: 2012 intake

Find out more about our Honours program or PhD program.

Browse the projects in the table or sort them by clicking the table headings.

As project details become available, they will be listed here. Please check back frequently.

Research Theme	Research Division	Research Project Title	Supervisor(s)
Infectious diseases	Immunology Immunology	Understanding the persistence of immunological memory	Associate Professor David Tarlinton Professor Phil Hodgkin
Chronic inflammatory diseases	Molecular Medicine Molecular Medicine	Investigation of the molecular mechanisms of hearing loss	Dr Rachel Burt Dr Marina Carpinelli
Chronic inflammatory diseases	Molecular Medicine Molecular Medicine	Investigation of the genetics of progressive hearing loss	Dr Rachel Burt Dr Marina Carpinelli
Infectious diseases	Infection and Immunity Molecular Immunology Molecular Immunology	Therapies to promote immune mediated clearance of HIV, hepatitis B virus and tuberculosis	Dr Marc Pellegrini Dr Gabrielle Belz Dr Axel Kailles
Infectious diseases	Infection and Immunity Infection and Immunity	Regulation of host cell invasion in Toxoplasma parasites	Dr Chris Tonkin Professor Alan Cowman
Infectious diseases	Infection and Immunity Infection and Immunity	Moving in and renovating: Understanding the role of malaria proteins in erythrocyte remodeling	Professor Alan Cowman Dr Justin Boddey
Infectious diseases	Infection and Immunity Chemical Biology Infection and Immunity	Plasmepsin V inhibitors as antimalarial agents	Dr Justin Boddey Dr Brad Sleebs Professor Alan Cowman
Infectious diseases	Infection and Immunity Infection and Immunity	Role of exported proteins in the intracellular dynamics of liver-stage malaria	Dr Justin Boddey Professor Alan Cowman
Infectious diseases	Infection and Immunity Infection and Immunity	Understanding how malaria parasites remodel the red blood cell of humans	Professor Alan Cowman Dr Justin Boddey
Infectious diseases	Infection and Immunity Infection and Immunity Structural Biology	Understanding the role of proteins in invasion of human red blood cellsby malaria parasites	Professor Alan Cowman Dr Tony Hodder Dr Peter Czabotar
Infectious diseases	Infection and Immunity Infection and Immunity Infection and Immunity	Understanding the structure and function of adhesins in invasion of malaria parasites	Professor Alan Cowman Dr Wai-Hong Tham Dr Tony Hodder
Cancer	Stem Cells and Cancer Stem Cells and Cancer	LMO4 in lung development and cancer	Dr Marie-Liesse Asselin-Labat Professor Jane Visvader
Cancer	Stem Cells and Cancer Stem Cells and Cancer	Preclinical validation of new combination therapies in xenograft mouse models of lung cancer	Dr Marie-Liesse Asselin-Labat Professor Geoff Lindeman
Infectious diseases	Molecular Immunology Molecular Immunology	The role of effector regulatory T cells in immunity and pathology	Dr Axel Kallies Dr Stephen Nutt
Cancer	Bioinformatics Bioinformatics	Systems biology for RNA-Seq and ChIP-Seq data	Professor Gordon Smyth To be advised.
Infectious diseases	Infection and Immunity Infection and Immunity	The role of chemokine networks in severe malaria and the control of parasite density	Dr Diana Hansen Associate Professor Louis Schofield
Infectious diseases	Infection and Immunity Infection and Immunity	Development of B cell memory and antibody responses to malaria	Dr Diana Hansen Associate Professor Louis Schofield
Cancer	Stem Cells and Cancer Stem Cells and Cancer Stem Cells and Cancer	Identification of microRNAs that regulate cell-fate decisions & differentiation in the mammary gland	Professor Jane Visvader Professor Geoff Lindeman Dr Bhupinder Pal
Cancer	Stem Cells and Cancer Bioinformatics	Pre-clinical analysis of therapies targeted to specific sub-types of epithelial ovarian cancer	Associate Professor Clare Scott Dr Matthew Wakefield
Chronic inflammatory diseases	Molecular Genetics of Cancer Molecular Genetics of Cancer	The role of NF-kB in the development of autoimmunity and cancer in FasL-Fas mutant mice	Dr Lorraine O'Reilly Professor Andreas Strasser
Infectious diseases	Inflammation Inflammation Inflammation	Screening for virus miRNA that target the host innate immune response and inflammation	Dr Seth Masters Dr Motti Gerlic Dr Ben Croker
Chronic inflammatory diseases	Inflammation Immunology	Targeting inflammation during islet transplantation	Dr Seth Masters Dr Robyn Sutherland
Cancer	Cell Signalling and Cell Death Molecular Genetics of Cancer Cell Signalling and Cell Death	The role of phosphorylation in the regulation of pro-apoptoic Bax	Dr Grant Dewson Dr Ruth Kluck Robert Ninnis
Cancer	Infection and Immunity Infection and Immunity	Complex dynamics of natural acquisition of host immune responses to P. falciparum and P.vivax in PNG	Professor Ivo Mueller Associate Professor Louis Schofield
Cancer	Cancer and Haematology Cancer and Haematology	Modelling the multi-step pathogenesis of T-cell leukaemia	Dr Matthew McCormack Professor Warren Alexander
Infectious diseases	Chemical Biology Chemical Biology	Discovering new treatments for debilitating parasitic diseases using medicinal chemistry	Associate Professor Jonathan Baell Dr Brad Sleebs
Infectious diseases	Chemical Biology Chemical Biology	Discovery of novel agents with dual trypanocidal and fungicidal activity to treat Chagas’ disease	Associate Professor Jonathan Baell Dr Brad Sleebs
Chronic inflammatory diseases	Molecular Genetics of Cancer Molecular Genetics of Cancer	How do apoptosis and anergy integrate to prevent autoimmune disease?	Dr Daniel Gray Professor Andreas Strasser
Cancer	Chemical Biology Chemical Biology	PAINS: Elucidation of mechanisms of action in inhibiting translation	Associate Professor Jonathan Baell Dr Chris Burns
Infectious diseases	Structural Biology Structural Biology	Targeting cell death pathways in parasites	Dr Doug Fairlie Dr Erinna Lee
Cancer	Chemical Biology Structural Biology	Design and structural characterisation of Bcl-2 inhibitors	Dr Guillaume Lessene Dr Peter Czabotar
Cancer	Chemical Biology Chemical Biology	Synthesis and mode of action studies of spirocyclic alkaloids	Dr Guillaume Lessene Dr Chris Burns
Cancer	Cancer and Haematology Cancer and Haematology	Contribution of platelets to cancer progression	Dr Emma Josefsson Dr Benjamin Kile
Chronic inflammatory diseases	Immunology Immunology	Improving drug therapies for immune diseases	Professor Phil Hodgkin Dr Susanne Heinzel
Infectious diseases	Structural Biology Structural Biology	Mechanics of transmembrane signalling in the immune system	Dr Matthew Call Dr Melissa Call
Cancer	Cancer and Haematology Molecular Genetics of Cancer	Programmed cell death and angiogenesis	Dr Leigh Coultas Professor Andreas Strasser
Infectious diseases	Structural Biology Structural Biology	How do immune regulatory enzymes recognise substrates inside the lipid bilayer?	Dr Matthew Call Dr Melissa Call
Cancer	Cell Signalling and Cell Death Cell Signalling and Cell Death	Cytokine signalling in myeloid leukaemia	Dr Anissa Jabbour Associate Professor Paul Ekert
Cancer	Chemical Biology Chemical Biology Chemical Biology	Synthesis and testing of novel covalent enzyme inhibitors	Dr Chris Burns Associate Professor Jonathan Baell Dr Kurt Lackovic
Infectious diseases	Infection and Immunity Infection and Immunity	How do malaria parasites signal for invasion?	Professor Alan Cowman Dr Wai-Hong Tham
Cancer	Chemical Biology Chemical Biology	Design and synthesis of selective kinase inhibitors	Dr Chris Burns Dr Guillaume Lessene
Cancer	Structural Biology Structural Biology	Ligand binding to the insulin-like growth factor receptor	Associate Professor Mike Lawrence Dr Jacqui Gulbis
Cancer	Chemical Biology Molecular Genetics of Cancer Chemical Biology	Development of fluorescently labeled Bcl-2 inhibitors	Dr Chris Burns Professor Andreas Strasser Professor David Huang
Cancer	Molecular Medicine Molecular Medicine	Generation of an inter-lineage cross-talk model of haematopoietic stem cell development	Dr Samir Taoudi Professor Doug Hilton
Cancer	Structural Biology Structural Biology	A novel strategy for understanding how insulin binds to its receptor	Associate Professor Mike Lawrence Dr Jacqui Gulbis
Cancer	Bioinformatics Bioinformatics	Computational methods and analysis of tumour genome sequence data	Dr Tony Papenfuss Professor Terry Speed
Infectious diseases	Bioinformatics Bioinformatics	Scabies mite genome project	Dr Tony Papenfuss Professor Terry Speed
Cancer	Chemical Biology Molecular Genetics of Cancer Personalised Medicine and Systems Biology	Identifying and validating novel targets for cancer therapy	Professor David Huang Professor Andreas Strasser Professor Liam O'Connor
Chronic inflammatory diseases	Molecular Immunology Molecular Immunology	Tgfb signalling in Blimp1-mediated T cell differentiation	Dr Axel Kallies Dr Stephen Nutt
Cancer	Chemical Biology Chemical Biology Chemical Biology	Identification of Novel Targets for Cancer Therapy	Dr Ian Street Dr Hendrik Falk Professor David Huang
Chronic inflammatory diseases	Molecular Medicine Molecular Medicine Cancer and Haematology	Investigating transcriptional regulation of eosinophil development	Dr Clare Morgan Professor Doug Hilton Professor Warren Alexander
Infectious diseases	Infection and Immunity Infection and Immunity	The molecular epidemiology of malaria transmission in the Southwest Pacific	Professor Ivo Mueller Dr Alyssa Barry
Infectious diseases	Infection and Immunity Infection and Immunity	Mapping malaria parasite population structure in the Asia-Pacific	Dr Alyssa Barry Professor Ivo Mueller
Cancer	Molecular Genetics of Cancer Molecular Genetics of Cancer	Regulating the mitochondrial pathway of apoptosis	Dr Ruth Kluck Dr Amber Alsop
Infectious diseases	Molecular Immunology Infection and Immunity Molecular Immunology	Understanding the generation of protective memory T cells	Dr Gabrielle Belz Dr Marc Pellegrini Dr Axel Kallies
Chronic inflammatory diseases	Molecular Immunology Molecular Immunology	Transcriptional regulation of innate immune cells protecting the intestinal tract	Dr Gabrielle Belz Dr Erika Cretney
Infectious diseases	Molecular Immunology Molecular Immunology Molecular Immunology	Epigenetic control of dendritic cell development and function	Dr Rhys Allan Dr Gabrielle Belz Dr Stephen Nutt
Infectious diseases	Infection and Immunity Infection and Immunity	Population biology of two newly identified species of human malaria parasite	Dr Alyssa Barry Dr Celine Barnadas
Chronic inflammatory diseases	Inflammation Cancer and Haematology	Targeted deletion of GM-CSF from immune cell populations and the effect on inflammatory arthritis	Professor Ian Wicks Professor Warren Alexander
Cancer	Cell Signalling and Cell Death Cell Signalling and Cell Death Cell Signalling and Cell Death	Analysis of CARP1 and CARP2 KO mice	Professor David Vaux Dr Najoua Lalaoui Dr James Vince
Cancer	Cancer and Haematology Cancer and Haematology	Understanding the interplay between JAK2 and SOCS3 in blood diseases	Dr Jeff Babon Dr James Murphy
Cancer	Cell Signalling and Cell Death Cell Signalling and Cell Death	How FADD connects TNF receptors to RIPK1 and RIPK3	Professor David Vaux Dr Kate Lawlor
Chronic inflammatory diseases	Cell Signalling and Cell Death Personalised Medicine and Systems Biology	Mapping the TNFR1 interactome	Associate Professor John Silke Dr Andrew Webb
Chronic inflammatory diseases	Structural Biology Structural Biology	Regulation of calcium signalling	Dr Jacqui Gulbis Associate Professor Mike Lawrence
Infectious diseases	Immunology Immunology	Exploring cellular calculation with the B lymphocyte model	Professor Phil Hodgkin Associate Professor David Tarlinton

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PhD and Honours research projects: 2012 intake

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