Kate Sutherland-Publications

Kate Sutherland-Publications

Researcher: 

Selected publications

  1. Serresi M, Gargiulo G, Proost N, Siteur B, Cesaroni M, Koppens M, Xie H, Sutherland KD, Hulsman D, Citterio E, Orkin S, Berns A and van Lohuizen M. Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer. Cancer Cell. 2016;29(1):17-31. PMID: 26766588 
  2. Kwon MC, Proost N, Song JY, Sutherland KD, Zevenhoven J and Berns A. Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis. Genes Dev. 2015;29(15):1587-92. PMID: 26215568
  3. Sutherland KD and Visvader JE. Cellular Mechanisms Underlying Intertumoral Heterogeneity. Trends in Cancer. 2015;1(1):15-23. 
  4. Sutherland KD, Song J-Y, Kwon MC, Proost N, Zevenhoven J, Berns A. Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma. Proceedings of the National Academy of Sciences. 2014 April 1, 2014;111(13):4952-7. PMID: 24586047
  5. Sutherland K, Proost N, Brouns I, Adriaensen D, Song JY, Berns A. Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell. 2011;19(6):754-64. PMID: 21665149
  6. Asselin-Labat ML, Sutherland KD, Vaillant F, Gyorki DE, Wu D, Holroyd S, Breslin K, Ward T, Shi W, Bath ML, Deb S, Fox SB, Smyth GK, Lindeman GJ, Visvader JE. Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. Molecular and Cellular Biology. 2011;31(22):4609-22. PMID: 21930782
  7. Sutherland KD and Berns A. Cell of origin of lung cancer. Molecular Oncology. 2010;4(5):397-403. PMID: 20594926
  8. Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, Hartley L, Robb L, Grosveld FG, van der Wees J, Lindeman GJ, Visvader JE. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nature Cell Biology. 2007;9(2):201-9. PMID: 17187062
  9. Sutherland KD, Vaillant F, Alexander WS, Wintermantel TM, Forrest NC, Holroyd SL, McManus EJ, Schutz G, Watson CJ, Chodosh LA, Lindeman GJ, Visvader JE. c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. EMBO Journal. 2006;25(24):5805-15. PMID: 17139252
  10. Sutherland KD, Lindeman GJ, Choong DYH, Wittlin S, Brentzell L, Phillips W, Campbell IG, Visvader JE. Differential hypermethylation of SOCS genes in ovarian and breast carcinomas. Oncogene. 2004;23(46):7726-33. PMID: 15361843