Jousset-Publications

Jousset-Publications

Lackovic K, Lessene G, Falk H, Leuchowius KJ, Baell J, Street I. A perspective on 10-years HTS experience at the Walter and Eliza Hall Institute of Medical Research - eighteen million assays and counting. Combinatorial chemistry & high throughput screening. 2014 Mar;17(3):241-52. PMID: 24409955

Sleebs BE, Kersten WJ, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, et al. Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL. Journal of medicinal chemistry. 2013 Jul 11;56(13):5514-40. PMID: 23767404

Sleebs BE, Gazdik M, O'Neill MT, Rajasekaran P, Lopaticki S, Lackovic K, et al. Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P. falciparum and P. vivax. Journal of medicinal chemistry. 2014 Sep 11. PMID: 25167370

Lessene G, Czabotar PE, Sleebs BE, Zobel K, Lowes KN, Adams JM, et al. Structure-guided design of a selective BCL-X(L) inhibitor. Nature chemical biology. 2013 Jun;9(6):390-7. PMID: 23603658

Sleebs BE, Czabotar PE, Fairbrother WJ, Fairlie WD, Flygare JA, Huang DC, et al. Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity. Journal of medicinal chemistry. 2011 Mar 24;54(6):1914-26. PMID: 21366295