Which anti-apoptotic Bcl-2 protein family members are critical for the development and sustained gro
Description of research project goes here – Using our panel of gene-targeted mice and transgenic mouse models of tumour development, we are investigating which anti-apoptotic Bcl-2 protein family members (Bcl-2, Bcl-xL, Bcl-w, Mcl-1, A1) are critical for the development and the sustained growth of tumours. Results from these studies are expected to provide valuable information for basic research and will assist translational and clinical research by pinpointing the proteins that need to be targeted for cancer therapy.