Intact protein or peptide mass determination by MALDI-TOF or LC-ESI-TOF
Protein identification by nanoHPLC-ESI-MS/MS
Characterisation of post-translational modifications (ie, phosphorylation, ubiquitinylation, glycosylation)
Expert analysis and manual validation of (tandem) mass spectrometric raw data
Unbiased quantitative proteomic analysis on a high mass-accuracy hybrid LTQ-Orbitrap platform for protein expression profiling and biomarker discovery
Targeted quantitative proteomic analysis on a fast, sensitive triple-quadrupole platform for multiple reaction monitoring (MRM) of pre-selected biomarkers
