Sequence : "PFFRM (EMBL)"
DNA "PFFRM (EMBL)" 843
Title "Plasmodium falciparum (clones BRA3-5b,-19a,-14b,-28e) liver stage-
specific antigen 1 (LSA-1) gene, 3' end of cds."
Entry_date 1995-04-13
Modification_date 1995-08-24
Database "EMBL" "PFFRM (EMBL)" "L40835"
DB_remark "1. Last author is Altaf A. Lal 2. The following clones have th
e sam e nucleotide sequence: BRA3-5b; BRA3-19a; BRA3-14b (one silent chan
ge at 5181, A to G) and BRA3-28e (one silent change at 5040, T to C) Clon
e name abbreviations: KEN for Kenya; PNG for Papua New Guinea and BRA for
 Brazil. For each clone, the number following the KEN, PNG or BRA represe
nts group number, the number following the '-' denotes the patient's bloo
d sample number and the lower case letter represents recombinant clones f
rom the corresponding isolates. NCBI gi: 725288"
Clone "BRA3-14b"
Organism "Plasmodium falciparum"
Clone "BRA3-19a"
Organism "Plasmodium falciparum"
Clone "BRA3-5b"
Organism "Plasmodium falciparum"
Clone "BRA3-28e"
Organism "Plasmodium falciparum"
Clone "BRA3-29b"
Organism "Plasmodium falciparum"
Keyword "exoerythrocytic"
Keyword "liver stage-specific antigen"
Keyword "liver stage-specific antigen 1"
Keyword "Malaria"
Subsequence  "PFFRM:CDS.1 (EMBL)" 1 843
mutation 1 843  "" Location "replace(75,'c')"
mutation 1 843  "" Note "clone BRA3-28e"
Locus "LSA-1"
mutation 1 843  "" Location "replace(216,'g')"
mutation 1 843  "" Note "clone BRA3-14b"
Locus "LSA-1"
Reference "Mol._Biochem._Parasitol._71:291-294(1995)."




DNA : "PFFRM (EMBL)"
aggaaggctgatacgaaaaaaaatttagaaagaaaaaaggaacatggagatgtattagca
gaggatttatatggtcgtttagaaataccagttatagaacttccatcagaaaatgaacgt
ggatattatataccacatcaatcttctttacctcaggacaacagagggaatagtagagat
tccaaggaaatatctataatagaaaaaacaaatagagaatctattacaacaaatgttgaa
ggacgaagggatatacataaaggacatcttgaagaaaagaaagatggttcaataaaacca
gaacaaaaagaagataaatctgctgacatacaaaatcatacattagagacagtaaatatt
tctgatgttaatgattttcaaataagtaagtatgaggatgaaataagtgctgaatatgac
gattcattaatagatgaagaagaagatgatgaagacttagacgaatttaagcctattgtg
caatatgacaatttccaagatgaagaaaacataggaatttataaagaactagaagatttg
atagagaaaaatgaaaatttagatgatttagatgaaggaatagaaaaatcatcagaagaa
ttatctgaagaaaaaataaaaaaaggaaagaaatatgaaaaaacaaaggataataatttt
aaaccaaatgataaaagtttgtatgatgagcatattaaaaaatataaaaatgttaagcag
gttaataaggaaaaggaaaaattcataaaatcattgtttcatatatttgacggagacaat
gaaattttacagatcgtggatgagttatctgaagatataactaaatattttatgaaacta
taa



Sequence : "PFFRM:CDS.1 (EMBL)"
Organism "Plasmodium falciparum"
Organism "Plasmodium falciparum"
Organism "Plasmodium falciparum"
Organism "Plasmodium falciparum"
Organism "Plasmodium falciparum"
Source "PFFRM (EMBL)"
Source_Exons 1 843
CDS
Remark "<1..843 \
/note='NCBI gi: 950674' \
/codon_start=1 \
/db_xref='PID:g950674' \
/db_xref='SPTREMBL:Q25853'"
Locus "LSA-1"
Corresponding_protein "liver stage-specific antigen 1"
Expr_pattern "PFFRM:CDS.1 (EMBL)"



Expr_pattern : "PFFRM:CDS.1 (EMBL)"
Sequence "PFFRM:CDS.1 (EMBL)"
Protein "liver stage-specific antigen 1"
Pattern "RKADTKKNLERKKEHGDVLAEDLYGRLEIPVIELPSENERGYYIP \
HQSSLPQDNRGNSRDSKEISIIEKTNRESITTNVEGRRDIHKGHLEEKKDGSIKPEQKE \
DKSADIQNHTLETVNISDVNDFQISKYEDEISAEYDDSLIDEEEDDEDLDEFKPIVQYD \
NFQDEENIGIYKELEDLIEKNENLDDLDEGIEKSSEELSEEKIKKGKKYEKTKDNNFKP \
NDKSLYDEHIKKYKNVKQVNKEKEKFIKSLFHIFDGDNEILQIVDELSEDITKYFMKL"



Protein : "liver stage-specific antigen 1"
Corresponding_DNA "PFFRM:CDS.1 (EMBL)"
Expr_pattern  "PFFRM:CDS.1 (EMBL)"



Paper : "Mol._Biochem._Parasitol._71:291-294(1995)."
Title "Sequence variations in the non-repetitive regions of the liver sta
ge-specific antigen-1 (LSA-1) of Plasmodium falciparum from field isolate
s"
Medline_ID
Journal "Mol. Biochem. Parasitol. 71:291-294(1995)."
Author "Yang C."
Author "Shi Y.P."
Author "Udhayakumar V."
Author "Alpers M.P."
Author "Povoa M.M."
Author "Hawley W.A."
Author "Collins W.E."
Author "Lal A.A."