P. falciparum erythrocyte membrane protein 1 (PfEMP-1)
  1. al-Khedery, B., J. W. Barnwell et al. (1999). "Antigenic variation in malaria: a 3' genomic alteration associated with the expression of a P. knowlesi variant antigen." Mol Cell 3(2): 131-41.

  2. Aley, S. B., J. W. Barnwell et al. (1984). "Identification of parasite proteins in a membrane preparation enriched for the surface membrane of erythrocytes infected with Plasmodium knowlesi." Mol Biochem Parasitol 12(69): 69-84.

  3. Aley, S. B., J. A. Sherwood et al. (1984). "Knob-positive and knob-negative Plasmodium falciparum differ in expression of a strain-specific malarial antigen on the surface of infected erythrocytes." J Exp Med 160: 1585-1590.

  4. Aley, S. B., J. A. Sherwood et al. (1986). "Identification of isolate-specific proteins on sorbitol-enriched Plasmodium falciparum infected erythrocytes from Gambian patients." Parasitology 92: 511-525.

  5. Allred, D. R. (1998). "Antigenic variation in Babesia bovis: how similar is it to that in Plasmodium falciparum?" Ann Trop Med Parasitol 92(4): 461-72.

  6. Aungst, M. (1998). "Receptor-specific adhesion and clinical disease in Plasmodium falciparum [letter; comment]." Am J Trop Med Hyg 58(3): 265.

  7. Barnwell, J. W., R. J. Howard et al. (1983). "Influence of the spleen on the expression of surface antigens on parasitized erythrocytes." Ciba Found Symp 94(117): 117-136.

  8. Barnwell, J. W., R. J. Howard et al. (1983). "Splenic requirement for antigenic variation and expression of the variant antigen on the erythrocyte membrane in cloned Plasmodium knowlesi malaria." Infect Immunity 40: 985-994.

  9. Barnwell, J. W., C. F. Ockenhouse et al. (1985). "Monoclonal antibody OKM5 inhibits the in vitro binding of Plasmodium falciparum-infected erythrocytes to monocytes, endothelial, and C32 melanoma cells." J Immunol 135: 3494-3497.

  10. Barnwell, J. W., A. S. Asch et al. (1989). "A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes." J Clin Invest 84(765): 765-772.

  11. Barragan, A., P. G. Kremsner et al. (1998). "Age-related buildup of humoral immunity against epitopes for rosette formation and agglutination in African areas of malaria endemicity." Infect Immun 66(10): 4783-7.

  12. Baruch, D. I., B. L. Pasloske et al. (1995). "Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes [see comments]." Cell 82(1): 77-87.

  13. Baruch, D. I., J. A. Gormely et al. (1996). "Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1." Proc Natl Acad Sci U S A 93(8): 3497-502.

  14. Baruch, D. I., X. C. Ma et al. (1997). "Identification of a region of PfEMP1 that mediates adherence of Plasmodium falciparum infected erythrocytes to CD36: conserved function with variant sequence." Blood 90(9): 3766-75.

  15. Biggs, B. A., J. G. Culvenor et al. (1989). "Plasmodium falciparum: cytoadherence of a knobless clone." Exp Parasitol 69(189): 189-197.

  16. Biggs, B. A., D. J. Kemp et al. (1989). "Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro." Proc Natl Acad Sci U S A 86: 2428-2432.

  17. Biggs, B. A., L. Goozé et al. (1990). "Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36." J Exp Med 171(6): 1883-1892.

  18. Biggs, B. A., L. Goozé et al. (1991). "Antigenic variation in Plasmodium falciparum." Proc Natl Acad Sci Usa 88(20): 9171-9174.

  19. Biggs, B. A., R. F. Anders et al. (1992). "Adherence of infected erythrocytes to venular endothelium selects for antigenic variants of Plasmodium falciparum." J Immunol 149(6): 2047-54.

  20. Borst, P., W. Bitter et al. (1995). "Antigenic variation in malaria [comment]." Cell 82(1): 1-4.

  21. Brown, K. N. (1989). Antigenic variation.

  22. Bull, P. C., B. S. Lowe et al. (1998). "Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria." Nat Med 4(3): 358-60.

  23. Bull, P. C., B. S. Lowe et al. (1999). "Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants." Infect Immun 67(2): 733-9.

  24. Chaiyaroj, S. C., R. L. Coppel et al. (1994). "A Plasmodium falciparum isolate with a chromosome 9 deletion expresses a trypsin-resistant cytoadherence molecule." Mol Biochem Parasitol 67(1): 21-30.

  25. Chen, Q., A. Barragan et al. (1998). "Identification of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) as the rosetting ligand of the malaria parasite P. falciparum." J Exp Med 187(1): 15-23.

  26. Chen, Q., V. Fernandez et al. (1998). "Developmental selection of var gene expression in Plasmodium falciparum." Nature 394(6691): 392-5.

  27. Cooke, B. M., C. L. Nicoll et al. (1998). "A recombinant peptide based on PfEMP-1 blocks and reverses adhesion of malaria-infected red blood cells to CD36 under flow." Mol Microbiol 30(1): 83-90.

  28. Crabb, B. S., B. M. Cooke et al. (1997). "Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress." Cell 89(2): 287-96.

  29. Fernandez, V., C. J. Treutiger et al. (1998). "Multiple adhesive phenotypes linked to rosetting binding of erythrocytes in Plasmodium falciparum malaria." Infect Immun 66(6): 2969-75.

  30. Fischer, K., P. Horrocks et al. (1997). "Expression of var genes located within polymorphic subtelomeric domains of Plasmodium falciparum chromosomes." Mol Cell Biol 17(7): 3679-86.

  31. Fujioka, H. and M. Aikawa (1996). "The molecular basis of pathogenesis of cerebral malaria." Microb Pathog 20(2): 63-72.

  32. Hasler, T., S. M. Handunnetti et al. (1990). "In vitro rosetting, cytoadherence, and microagglutination properties of Plasmodium falciparum-infected erythrocytes from Gambian and Tanzanian patients." Blood 76(9): 1845-1852. Reference Number: 856; Reference Type: Article

  33. Hayward, R. E., B. Tiwari et al. (1999). "Virulence and transmission success of the malarial parasite Plasmodium falciparum." Proc Natl Acad Sci U S A 96(8): 4563-8.

  34. Ho, M., T. Schollaardt et al. (1998). "Characterization of Plasmodium falciparum-infected erythrocyte and P- selectin interaction under flow conditions." Blood 91(12): 4803-9.

  35. Hommel, M., P. H. David et al. (1982). "Expression of strain- specific surface antigens on Plasmodium falciparum-infected erythrocytes." Parasite Immunol 4: 409-419.

  36. Hommel, M., P. H. David et al. (1983). "Surface alterations of erythrocytes in Plasmodium falciparum malaria." J Exp Med 157: 1137-1148.

  37. Hommel, M. (1985). "The role of variant antigens in acquired immunity to Plasmodium falciparum." Ann Soc Belg Med Trop 65(57): 57-67.

  38. Hommel, M. (1985). "Antigenic variation in malaria parasites." Immunol Today 6: 28-33.

  39. Hommel, M. and S. Semoff (1988). "Expression and function of erythrocyte-associated surface antigens in malaria." Biol Cell 64: 183-203.

  40. Hommel, M. (1990). "Cytoadherence of malaria-infected erythrocytes." Blood Cells 16(2-3): 605-619. Reference Number: 763; Reference Type: Article

  41. Howard, R. J. and J. W. Barnwell (1984). "Roles of surface antigens on malaria-infected red blood cells in evasion of immunity." Contemp Top Immunobiol 12(127): 127-200.

  42. Howard, R. J. (1984). "Antigenic variation of bloodstage malaria parasites." Phil Trans Roy Soc Lond :Biol B307: 141-158.

  43. Howard, R. J. and J. W. Barnwell (1984). "Solubilization and immunoprecipitation of 125I-labelled antigens from Plasmodium knowlesi schizont-infected erythrocytes using non-ionic, anionic and zwitterionic detergents." Parasitology 88: 27-36.

  44. Howard, R. J. and J. W. Barnwell (1985). "Immunochemical analysis of surface membrane antigens on erythrocytes infected with non- cloned SICA:+: or cloned SICA:-: Plasmodium knowlesi." Parasitology 91: 245-261.

  45. Howard, R. F., H. A. Stanley et al. (1985). "Two Plasmodium falciparum merozoite surface polypeptides share epitopes with a single Mr 185 000 parasite glycoprotein." Mol Biochem Parasitol 17: 61-77.

  46. Howard, R. J., J. S. McBride et al. (1986). "Antigenic diversity and size diversity of P. falciparum antigens in isolates from Gambian patients. II. the schizont surface glycoprotein of molecular weight approximately 200 000." Parasite Immunol 8: 57- 68.

  47. Howard, R. J., S. Uni et al. (1986). Export of Plasmodium falciparum proteins to the host erythrocyte membrane: Special problems of protein trafficking and topogenesis. New York, Plenum Press.

  48. Howard, R. J. (1987). "Antigenic variation and antigenic diversity in malaria." Contrib Microbiol Immunol 8(176): 176-218.

  49. Howard, R. J., J. W. Barnwell et al. (1988). "Two approximately 300 kilodalton Plasmodium falciparum proteins at the surface membrane of infected erythrocytes." Mol Biochem Parasitol 27(2-3): 207-23.

  50. Howard, R. J. (1988). "Malarial proteins at the membrane of Plasmodium falciparum-infected erythrocytes and their involvement in cytoadherence to endothelial cells." Prog Allergy 41: 98-147.

  51. Howard, R. J. (1988). "Plasmodium falciparum proteins at the host erythrocyte membrane: Their biological and immunological significance and novel parasite organelles which deliver them to the cell surface." Biol Parasitism: 111-145.

  52. Howard, R. J. and A. D. Gilladoga (1989). "Molecular studies related to the pathogenesis of cerebral malaria." Blood 74(8): 2603-18.

  53. Howard, R. J., S. M. Handunnetti et al. (1990). "Surface molecules on Plasmodium falciparum-infected erythrocytes involved in adherence." Am J Trop Med Hyg 43(2): 15-29.

  54. Jakobsen, P. H., V. McKay et al. (1998). "Decreased antitoxic activities among children with clinical episodes of malaria." Infect Immun 66(4): 1654-9.

  55. Leech, J. H., S. B. Aley et al. (1984). "Plasmodium falciparum malaria: cytoadherence of infected erythrocytes to endothelial cells and associated changes in the erythrocyte membrane." Prog Clin Biol Res 155(63): 63-77.

  56. Leech, J. H., J. W. Barnwell et al. (1984). "Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes." J Exp Med 159: 1567- 1575.

  57. Marsh, K. and R. J. Howard (1986). "Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinants." Science 231: 150-153.

  58. Marsh, K., J. A. Sherwood et al. (1986). "Parasite-infected-cell- agglutination and indirect immunofluorescence assays for detection of human serum antibodies bound to antigens on Plasmodium falciparum-infected erythrocytes." J Immunol Methods 91(1): 107- 115.

  59. Marsh, K., L. Otoo et al. (1989). "Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection." Trans Roy Soc Trop Med Hyg 83(3): 293-303.

  60. Newbold, C. I., A. G. Craig et al. (1997). "PfEMP1, polymorphism and pathogenesis." Ann Trop Med Parasitol 91(5): 551-7.

  61. Nowak, R. (1995). "Malaria. How the parasite disguises itself [news]." Science 269(5225): 755.

  62. Ockenhouse, C. F. and J. D. Chulay (1988). "Plasmodium falciparum sequestration: OKM5 antigen (CD36) mediates cytoadherence of parasitized erythrocytes to a myelomonocytic cell line." J Infect Dis 157(584): 584-588.

  63. Ockenhouse, C. F., F. W. Klotz et al. (1991). "Sequestrin, a CD36 recognition protein on Plasmodium falciparum malaria-infected erythrocytes identified by anti-idiotype antibodies." Proc Natl Acad Sci Usa 88(8): 3175-3179.

  64. Ockenhouse, C. F., M. Ho et al. (1991). "Molecular basis of sequestration in severe and uncomplicated Plasmodium falciparum malaria: Differential adhesion of infected erythrocytes to CD36 and ICAM-1." J Infect Dis 164(1): 163-169.

  65. Pasloske, B. L. and R. J. Howard (1994). "Malaria, the red cell, and the endothelium." Annu Rev Med 45: 283-95.

  66. Piper, K. P., D. J. Roberts et al. (1999). "Plasmodium falciparum: analysis of the antibody specificity to the surface of the trophozoite-infected erythrocyte." Exp Parasitol 91(2): 161-9.

  67. Pouvelle, B., T. Fusai et al. (1998). "[Plasmodium falciparum and chondroitin-4-sulfate: the new key couple in sequestration]." Med Trop 58(2): 187-98.

  68. Preiser, P. R., W. Jarra et al. (1999). "A rhoptry-protein- associated mechanism of clonal phenotypic variation in rodent malaria [see comments]." Nature 398(6728): 618-22.

  69. Reeder, J. C., A. F. Cowman et al. (1999). "The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1." Proc Natl Acad Sci U S A 96(9): 5198-202.

  70. Rowe, J. A., J. M. Moulds et al. (1997). "P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1." Nature 388(6639): 292-5.

  71. Scherf, A., R. Hernandez-Rivas et al. (1998). "Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum." Embo J 17(18): 5418-26.

  72. Schmidt, J. A., I. J. Udeinya et al. (1982). "Plasmodium falciparum malaria. An amelanotic melanoma cell line bears receptors for the knob ligand on infected erythrocytes." J Clin Invest 70: 379-386.

  73. Sharma, Y. D. (1991). "Knobs, knob proteins and cytoadherence in falciparum malaria." Int J Biochem 23(9): 775-89.

  74. Sharma, Y. D. (1997). "Knob proteins in falciparum malaria." Indian J Med Res 106: 53-62.

  75. Sherman, I. W. and E. Valdez (1989). "In vitro cytoadherence of Plasmodium falciparum-infected erythrocytes to melanoma cells: factors affecting adhesion." Parasitology 98: 359-369.

  76. Sherwood, J. A., K. Marsh et al. (1985). "Antibody mediated strain-specific agglutination of Plasmodium falciparum-parasitized erythrocytes visualized by ethidium bromide staining." Parasite Immunol 7: 659-663.

  77. Sherwood, J. A., D. D. Roberts et al. (1986). "Parasitized erythrocyte antigens and thrombospondin adhesion in the immunology and pathogenesis of falciparum malaria." Trans Assoc Am Physicians 99(206): 206-213.

  78. Sherwood, J. A., S. L. Spitalnik et al. (1986). "Plasmodium falciparum and P. knowlesi: initial identification and characterization of malaria synthesized glycolipids." Exp Parasitol 62(127): 127-141.

  79. Sherwood, J. A., D. D. Roberts et al. (1987). "Thrombospondin binding by parasitized erythrocyte isolates in falciparum malaria." Am J Trop Med Hyg 36: 228-233.

  80. Sherwood, J. A., D. D. Roberts et al. (1989). "Studies of the receptors on melanoma cells for Plasmodium falciparum infected erythrocytes." Am J Trop Med Hyg 40: 119-127.

  81. Sherwood, J. A. (1990). "Cytoadherence of malaria-infected erythrocytes. Commentary: Progress toward understanding the pathogenesis of sequestration in falciparum malaria." Blood Cells 16(2-3): 620-628. Reference Number: 764; Reference Type: Editorial

  82. Sherwood, J. A., D. D. Roberts et al. (1990). "Falciparum malaria parasitized erythrocytes bind to a carboxy-terminal thrombospondin fragment and not the amino-terminal heparin-binding region." Mol Biochem Parasitol 40: 173-182.

  83. Southwell, B., G. V. Brown et al. (1989). "Field applications of agglutination and cytoadherence assays with Plasmodium falciparum from Papua New Guinea." Trans Roy Soc Trop Med Hyg 83.

  84. Staalso, T., E. A. Khalil et al. (1998). "Antibody reactivity to conserved linear epitopes of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)." Immunol Lett 60(2-3): 121-6.

  85. Su, X. Z., V. M. Heatwole et al. (1995). "The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes [see comments]." Cell 82(1): 89-100.

  86. Targett, G. A. (1998). "Malaria--variety is the price of life [news]." Nat Med 4(3): 267-8.

  87. Turner, G. (1997). "Cerebral malaria." Brain Pathol 7(1): 569-82.

  88. Udeinya, I. J., J. A. Schmidt et al. (1981). "Falciparum malaria- infected erythrocytes specifically bind to cultured human endothelial cells." Science 213: 555-557.

  89. Udeinya, I. J., P. M. Graves et al. (1983). "Plasmodium falciparum: Effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells." Exp Parasitol 56: 207-214.

  90. Udeinya, I. J., L. H. Miller et al. (1983). "Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cells." Nature 303: 429-431.

  91. Udeinya, I. J., J. Leech et al. (1985). "An in vitro assay for sequestration: binding of Plasmodium falciparum-infected erythrocytes to formalin-fixed endothelial cells and amelanotic melanoma cells." J Protozool 32: 88-90.

  92. Udeinya, I. J. (1990). "In vitro and ex-vivo models of sequestration in Plasmodium falciparum infection." Am J Trop Med Hyg Reference Number: 228; Reference Type: Article

  93. Udomsangpetch, R., M. Aikawa et al. (1989). "Cytoadherence of knobless Plasmodium falciparum-infected erythrocytes and its inhibition by a human monoclonal antibody." Nature 338: 763-765.